Christina Applegate vows to fight for MS community despite misdiagnosis: ‘Still your warrior’
NEW YORK CITY, NEW YORK: Christina Applegate is standing by the people who became close to her during a difficult chapter of her health journey, even after learning that her diagnosis was incorrect.
The actor has shared an emotional message for the multiple sclerosis (MS) community, making it clear that her support for them will never change.
At the same time, Applegate is dealing with symptoms from an illness that doctors are yet to identify. The ‘Hall Pass’ star shared that her health condition is currently making her struggle with basic everyday movements.

Christina Applegate promises to remain an MS advocate despite misdiagnosis
Applegate is making it clear that learning she was misdiagnosed with multiple sclerosis will not change her connection with the people living with the condition. During the October 27 episode of her 'MeSsy' podcast, which she co-hosts with Jamie-Lynn Sigler, the actor shared an emotional message for listeners who have supported her throughout her health journey.
“Even though I don’t have this disease, I’ve fallen in love with everyone that we know, our listeners, our friends that have MS. I’m still your warrior, and I’m still going to speak out on your behalf forever and ever. Despite not having MS, I still feel like part of this community. No matter what, I love you,” Applegate said.
Christina Applegate vows to keep fighting for the MS community after being misdiagnosed with the disease. "Even though I don’t have this disease, I’ve fallen in love with everyone that we know, our listeners, our friends that have MS. I’m still your warrior, and I’m still going to speak out on your behalf forever and ever. Despite not having MS. I still feel like part of this community. No matter what, I love you." Applegate is now facing symptoms of an undiagnosed illness, explaining: "I actually timed it today, it took me 10 minutes to be able to move off my pillow and get out of the bed and stand up, at which point I almost couldn’t walk to the bathroom, and now a walker is sitting next to my bed because of what’s going on. I don’t know what’s going on. This is what I’m still living with, and I never had that before. I was able to sit up and stuff.” (via "MesSy") https://t.co/4sQqb37C3m
— Variety (@Variety) October 27, 2026
The 'Dead to Me' star previously revealed that her doctor informed her she was misdiagnosed with MS after spending years believing she was living with the condition. Applegate first announced her diagnosis in 2021 and became an outspoken advocate for people battling the disease.
Her latest comments show that she still wants to stand alongside the MS community, even while navigating her own condition.
Christina Applegate describes worsening symptoms as she searches for answers
While Applegate is determined to continue supporting the MS community, she is also facing difficult symptoms from an illness that doctors are yet to identify. In the same podcast episode, she described how even the simplest daily tasks have become challenging for her over the years.

“I actually timed it today, it took me 10 minutes to be able to move off my pillow and get out of the bed and stand up, at which point I almost couldn’t walk to the bathroom, and now a walker is sitting next to my bed because of what’s going on. I don’t know what’s going on," she shared.
"This is what I’m still living with, and I never had that before. I was able to sit up and stuff,” Applegate shared.