'He's quite ill': Rosie O'Donnell invokes 25th Amendment after Trump posts AI attack video

Trump posted AI video of him as doctor treating critics’ ‘derangement syndrome’
Rosie O'Donnell made blunt comments about Donald Trump after his AI video (X @RedWavePress/Getty Images)
Rosie O'Donnell made blunt comments about Donald Trump after his AI video (X @RedWavePress/Getty Images)

WASHINGTON, DC: The comedian and outspoken Trump critic, Rosie O'Donnell, escalated her decades-long feud with President Donald Trump by invoking the 25th Amendment after an official White House account shared an AI-generated video mocking her.

Her response sharply raised the stakes in one of Trump's longest-running celebrity feuds. It came after the White House amplified a video portraying AI versions of several Hollywood critics praising an AI-rendered Trump.

Rosie O'Donnell attends Cool Comedy Hot Cuisine Benefitting The Scleroderma Research Foundation at Fairmont Century Plaza on October 29, 2024 in Los Angeles, California. (Photo by Alberto E. Rodriguez/Getty Images)
Rosie O'Donnell attends Cool Comedy Hot Cuisine Benefitting The Scleroderma Research Foundation at Fairmont Century Plaza on October 29, 2024 in Los Angeles, California (Alberto E Rodriguez/Getty Images)

Rosie O'Donnell calls Trump ‘quite ill’

The Guardian on Thursday, July 2, asked O'Donnell whether she wanted to respond after Trump posted the AI-generated video on social media.

The comedian and former talk show host replied with a blistering statement aimed directly at the president.

"He's quite ill — and getting worse daily," O'Donnell said. "The 25th amendment exists for exactly this reason. Remove. Impeach. Convict."

President Donald Trump leaves the stage after speaking at the Burning Hills Amphitheater during the Theodore Roosevelt Presidential Library opening ceremony Wednesday, July 1, 2026. (AP Photo/Matt Rourke)
President Donald Trump leaves the stage after speaking at the Burning Hills Amphitheater during the Theodore Roosevelt Presidential Library opening ceremony Wednesday, July 1, 2026 (AP Photo/Matt Rourke)

Her remarks marked the newest escalation in a feud that has stretched across roughly two decades, with Trump repeatedly criticizing O'Donnell in public.

The AI-generated clip shared by an official White House account featured fabricated testimonials from AI versions of O'Donnell and fellow Trump critics John Leguizamo, Whoopi Goldberg, Ed Norton, Robert De Niro and Julia Roberts.

In the video, the AI-generated celebrities appear to praise an AI-rendered Trump, depicted wearing a white doctor's lab coat, for supposedly treating them.

Trump's AI post revives old feud

The latest exchange revived one of Trump's longest-running public disputes with a celebrity critic.

After Trump attacked O'Donnell during the first Republican presidential primary debate in 2015, she resurfaced a YouTube clip from a 2006 episode of ‘The View’ that she said, nearly a decade later, Trump "can't seem to get over."



In that clip, O'Donnell mocked Trump for holding a news conference announcing he would not strip a Miss USA contestant of her title after reports she had been dr**king and using d**gs.

After performing an impression of Trump, she said, "He annoys me on a multitude of levels."

O'Donnell also criticized his personal conduct, saying, "He's the moral authority: left the first wife, had an affair, left the second wife, had an affair, had kids both times, but he's the moral compass for 20-year-olds in America."

Robert De Niro attends the Savage Salvation Premiere at Helen Mills Theater on November 27, 2022 in New York City. (Getty)
Robert De Niro attends the Savage Salvation Premiere at Helen Mills Theater on November 27, 2022 in New York City (Getty Images)

Comedian revisits earlier Trump criticism

The 2006 segment also targeted Trump's business record.

"This is not a self-made man," O'Donnell said while arguing that he inherited wealth from his father and repeatedly relied on bankruptcy laws rather than paying creditors.

"I just think that this man is like sort of one of those, you know, snake-oil salesmen," she added.

Nearly two decades after that television exchange, and now with Trump serving as president, he posted the AI-generated video attacking O'Donnell from the official White House account.

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