Christina Applegate fears breast implants may be 'poisoning' her amid MS misdiagnosis
LOS ANGELES, CALIFORNIA: Christina Applegate is still searching for answers about her health problems. The actress recently shared another possibility she wants to explore, wondering whether her breast implants could be contributing to her symptoms.
Applegate discussed the concern during a new episode of her podcast, 'MeSsy', with co-host Jamie-Lynn Sigler.
She revealed that she has wondered for years whether her implants could be leaking and making her sick.

Christina Applegate questions breast implant complications
During the November 10 episode of 'MeSsy', Applegate, 54, said she had been considering the possibility for several years.
The actress underwent a double mastectomy in 2008 following her breast cancer diagnosis. Implants were later used as part of her breast reconstruction.
The actress said she is now overdue to have them replaced. She also recalled wondering whether a possible leak could be contributing to some of her health problems.
“I swear, over the last five years I thought, 'What if they're leaking and they're poisoning me?'” Applegate said. She also came across a study suggesting that the two conditions could have similar symptoms.
“So that's one that I will be looking into, because it's something I've thought about,” she added.
Christina Applegate says breast implant may have caused MS-like symptoms. https://t.co/u9Tbam0w09
— TMZ (@TMZ) November 10, 2026
Applegate has not confirmed that her implants are responsible for her symptoms. She plans to discuss the possibility with her doctors as she continues searching for an explanation.
“I don’t know what’s going on in my joints, but I can’t move my right shoulder like at all now. I can’t lift my arm,” she said.
“It’s overwhelming because there’s so many different things that could be going on, and this pain stuff,” she concluded.
Applegate undergoes tests after MS misdiagnosis
On the November 3 episode of 'MeSsy', Applegate discussed undergoing further tests to investigate conditions that could cause symptoms similar to those of multiple sclerosis (MS).
“We’re going in to square one, just doing some testing and going one by one of kind of the sister diseases to MS,” she said.
“You’ve got RA (rheumatoid arthritis), and you’ve got lupus and Lyme disease and all these things that kind of can mimic MS,” she explained. “So, now I’m being tested for all that stuff, slowly but surely.”

During the October 27 episode of her 'MeSsy' podcast, Applegate said, “Even though I don’t have this disease, I’ve fallen in love with everyone that we know, our listeners, our friends that have MS."
"I’m still your warrior, and I’m still going to speak out on your behalf forever and ever. Despite not having MS, I still feel like part of this community. No matter what, I love you."