Cassidy braces for Louisiana reckoning as impeachment vote comes back to haunt him

Senator Bill Cassidy battles Trump-backed rivals in a pivotal GOP primary, testing the future of one of the party's last impeachment supporters
Sen Bill Cassidy campaigns for a third Senate term amid a fierce GOP primary against Donald Trump backed Rep Julia Letlow and Louisiana State Treasurer John Fleming (Getty Images, AP Images)
Sen Bill Cassidy campaigns for a third Senate term amid a fierce GOP primary against Donald Trump backed Rep Julia Letlow and Louisiana State Treasurer John Fleming (Getty Images, AP Images)

WASHINGTON, DC: Republican Sen Bill Cassidy faces perhaps the toughest political test of his career on Saturday, May 16, as Louisiana Republicans cast their verdict on the senator for the first time since he voted to convict President Donald Trump during the 2021 impeachment trial following the January 6 Capitol riot.

Cassidy, seeking a third term in the Senate, is locked in a fierce Republican primary contest against Trump-endorsed Rep Julia Letlow and Louisiana State Treasurer John Fleming.

If no candidate secures more than 50% of the vote, the top two finishers will advance to a runoff election on June 27.

The race has become a defining test of whether Republicans who broke with Trump during his second impeachment can still survive politically in today’s GOP.

President Donald Trump answers questions from reporters after signing an executive order in the Oval Office of the White House Tuesday, March 31, 2026, in Washington. (AP Photo/Alex Brandon)
President Donald Trump answers questions from reporters after signing an executive order in the Oval Office of the White House, Tuesday, March 31, 2026, in Washington (AP Photo/Alex Brandon)

Trump throws support behind Julia Letlow

On the eve of the primary, President Donald Trump publicly endorsed Letlow in a post on Truth Social, praising her as a “TOTAL WINNER” and highlighting her record in Louisiana.

“I know Julia well, have seen her tested at the highest and most difficult levels,” Trump wrote, calling her “a wonderful person” who has “always delivered for Louisiana.”



Though Trump stopped short of directly attacking Cassidy in the latest post, the former president has repeatedly criticized Republicans who supported impeachment efforts against him.

Letlow has embraced Trump’s backing throughout the campaign, positioning herself as the candidate most aligned with the president’s agenda and the broader MAGA movement.

WASHINGTON, DC - FEBRUARY 12: Senator Bill Cassidy (R-LA) talks to reporters in the Senate subway on
Senator Bill Cassidy talks to reporters in the Senate subway on his way to the fourth day of the Senate's second impeachment trial of former President Donald Trump at the US Capitol on February 12, 2021, in Washington, DC (Samuel Corum/Getty Images)

Bill Cassidy defends record and says he works with Trump

Cassidy has acknowledged that his impeachment vote could hurt him politically, but he has attempted to shift voter focus toward his legislative accomplishments and influence in Washington.

The senator, currently chair of the Senate Health, Education, Labor and Pensions Committee, has argued that his effectiveness and experience distinguish him from his rivals.

“Bill Cassidy has been a terrific senator for Louisiana,” Senate Majority Leader John Thune told reporters Thursday, underscoring support from Senate Republican leadership.

Cassidy has also maintained that he continues to work effectively with Trump despite their past differences.

PALM BEACH, FLORIDA - JANUARY 09: Louisiana Gov. Jeff Landry speaks during a meeting with President Donald Trump and other Republican governors at the Mar-a-Lago Club on January 09, 2025 in Palm Beach, Florida (Photo by Scott Olson/Getty Images)
Louisiana Gov Jeff Landry speaks during a meeting with President Donald Trump and other Republican governors at the Mar-a-Lago Club on January 9, 2025, in Palm Beach, Florida (Scott Olson/Getty Images)

Louisiana primary changes complicate race

The election is unfolding under Louisiana’s newly revamped primary system after Gov Jeff Landry signed legislation replacing the state’s traditional “jungle primary” with closed party primaries.

Cassidy and his campaign have sharply criticized the changes, arguing that they disadvantage independent and unaffiliated voters who may have supported him.

“People are calling my office to say they tried to vote for me, but they could not,” Cassidy said during a Friday call with reporters. “People are confused … It’s a terrible system for this election.”



His campaign accused Landry of interfering in the contest to benefit Letlow, who is backed by the governor.

Meanwhile, Landry also postponed Louisiana’s House primaries while lawmakers redraw congressional maps after the Supreme Court invalidated existing district boundaries. The Senate race, however, remained on schedule.

HOLLYWOOD, CALIFORNIA - JANUARY 13: Robert F. Kennedy, Jr. speaks onstage at Food & Bounty At Sunset
Robert F Kennedy Jr speaks onstage at Food & Bounty at Sunset Gower Studios on January 13, 2019, in Hollywood, California (Joe Scarnici/Getty Images)

Bill Cassidy clashes with RFK Jr allies and the MAHA movement

Beyond impeachment, Cassidy has increasingly found himself at odds with factions closely aligned with Trump’s political coalition.

The senator publicly sparred with Health Secretary Robert F Kennedy Jr over vaccine skepticism, despite ultimately casting the deciding vote to confirm Kennedy to the Cabinet.

Earlier this month, Trump blamed Cassidy for blocking the confirmation prospects of surgeon general nominee Casey Means, forcing the administration to move toward another nominee.

WASHINGTON, DC - JUNE 24: Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. testifies before the House Energy and Commerce Committee Health Subcommittee in the Rayburn House Office Building on June 24, 2025 in Washington, DC. The committee met to hear testimony on the FY2026 Department of Health and Human Services budget. (Photo by Kayla Bartkowski/Getty Images)
Health and Human Services (HHS) Secretary Robert F Kennedy Jr testifies before the House Energy and Commerce Committee Health Subcommittee in the Rayburn House Office Building on June 24, 2025, in Washington, DC (Kayla Bartkowski/Getty Images)

Those tensions have made Cassidy a prime target of Kennedy’s 'Make America Healthy Again' movement. A pro-MAHA political action committee has poured hundreds of thousands of dollars into efforts supporting Letlow and attacking Cassidy.

The Louisiana Senate contest has become one of the most expensive Republican primaries of the year, with total spending surpassing $30 million.

According to ad-tracking firm AdImpact, pro-Cassidy advertising has reached nearly $22 million, while groups supporting Letlow have spent close to $10 million. Pro-Fleming efforts have added another $1.5 million to the race.

WASHINGTON, DC - FEBRUARY 13: U.S. President Donald Trump, Robert F. Kennedy Jr., and Kennedy's wife Cheryl Hines pose after Kennedy was sworn in as Secretary of Health and Human Services in the Oval Office at the White House on February 13, 2025 in Washington, DC. Kennedy, who faced criticism for his past comments on vaccine, was confirmed by the Senate 52 to 48. Former Senate Republican Leader Mitch McConnell (R-KY) was the only Republican to vote against him. (Photo by Andrew Harnik/Getty Images)
President Donald Trump, Robert F Kennedy Jr, and Kennedy's wife, Cheryl Hines, pose after Kennedy was sworn in as Secretary of Health and Human Services in the Oval Office at the White House on February 13, 2025, in Washington, DC (Andrew Harnik/Getty Images)

In the closing stretch, Letlow heavily embraced MAHA messaging, while Cassidy attacked her over stock trades and previous support for diversity, equity and inclusion initiatives during her tenure at the University of Louisiana.

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