Kris Jenner says she became 'so sick' after taking Ozempic: 'I can’t work anymore'

LOS ANGELES, CALIFORNIA: Media personality Kris Jenner has opened up about her experience using Ozempic, revealing that the medication caused severe side effects that left her unable to continue working. 

During a recent appearance on the 'SheMD' podcast, the Kardashian family matriarch admitted she tried the GLP-1 medication before it became widely popular but quickly stopped after experiencing intense nausea and sickness.

Kris Jenner recalls severe Ozempic side effects

Speaking candidly on the podcast on Tuesday, May 5, Jenner revealed that her first experience with Ozempic left her feeling extremely unwell. “We tried it once when no one knew what it was, and it made me really sick,” Jenner said.

The 70-year-old television personality explained that the side effects soon became overwhelming, prompting her to contact Dr. Thais Aliabadi, also known as Dr. A, one of the hosts of 'SheMD' and Jenner’s personal physician.

“I called her up one day,” Jenner recalled, “and I go, ‘I can't work anymore. I can't, I'm so sick. I can't like—nauseous.’ And so she goes, ‘Okay, okay, let's try something else.’”

Following the difficult experience, Jenner said she and Dr. Aliabadi “dialed around and looked at different options” before deciding on a combination of unspecified peptide injections, separate from Ozempic and other GLP-1 medications, along with supplements.

She claimed, “And that was a game changer. That actually bought me an extra couple of hours at night. Because I get up so early, I tend to want to go and collapse as soon as I have my last email or my last call or see my kids and have dinner and I'm done.”

Jenner added that the new wellness routine noticeably improved her energy levels and overall appearance. “I felt like I had more energy,” she said. “And of course, it’s good for hair, and nails, and skin, and all of that stuff.”

Kris Jenner discusses hormone health around Ozempic

For Jenner, closely monitoring her hormone health has become an important part of her wellness routine. She explained, “I get my blood drawn every three months, just to keep my hormones balanced. Because I realized after I was 45 that was like so important to just your physical female health—and male health, by the way. I encourage my son to check hormones to see what's happening."

She added, “But it was really a game changer for me, because when you look at your thyroid, you look at your hormone health—you look at what your body needs.” Jenner also joked that, beyond health and wellness routines, she “had a very well-known facelift a year ago,” adding that the procedure had been “helpful.”

Jenner’s comments come amid continuing public discussion surrounding GLP-1 medications, including Ozempic, which belongs to a class of drugs commonly containing semaglutide. The medication was originally approved by the FDA in 2017 to treat type II diabetes and works by promoting insulin production, lowering blood sugar levels, and reducing appetite.

These effects have also contributed to its growing popularity as a weight-loss treatment. Several celebrities have publicly shared their experiences with GLP-1 medications over the past few years. Among them is tennis star Serena Williams, who previously addressed criticism surrounding the use and promotion of the injections.

Speaking to PEOPLE last August, Williams said she felt “good and healthy” while receiving the medication once per week. Reflecting on her post-pregnancy weight-loss struggles after welcoming daughter Alexis Olympia in 2017, Williams explained, “I'd never been in a place like that in my life where I worked so hard, ate so healthy and could never get down to where I needed to be at.”

Serena added, “I had never taken shortcuts in my career and always worked really hard. I know what it takes to be the best, so it was very frustrating to do all the same things and never be able to change that number on the scale or the way my body looked.”