Thune backs 'regime change' in Iran as Trump reviews military 'contingencies'

'The president, I don't think, to my knowledge, has made any decisions, but I think they're gaming out what contingencies might look like', Thune said
UPDATED FEB 26, 2026
Senate Majority Leader John Thune said contingency planning was underway and argued that any military move must deliver 'transformational change' in the region (Getty Images)
Senate Majority Leader John Thune said contingency planning was underway and argued that any military move must deliver 'transformational change' in the region (Getty Images)

WASHINGTON, DC: Senate Majority Leader John Thune said on Thursday, February 26, that if the United States carries out military strikes against Iran, the objective should extend beyond limited action and aim at replacing the country’s leadership.

His remarks come amid rising expectations in Washington that President Donald Trump could authorize military action if diplomatic efforts failed to curb Iran’s nuclear program.

The comments were made as US and Iranian delegations met in Geneva for another round of negotiations.

Thune said that no final decision has been made, but indicated that contingency planning was underway. “In my view, if you’re going to do something there, you'd better well make it about getting new leadership and regime change,” he said.

U.S. President Donald Trump delivers his State of the Union address during a Joint Session of Congress at the U.S. Capitol on February 24, 2026, in Washington, DC. Trump delivered his address days after the Supreme Court struck down the administration's tariff strategy and amid a U.S. military buildup in the Persian Gulf threatening Iran. (Andrew Harnik/Getty Images)
President Donald Trump delivers his State of the Union address during a Joint Session of Congress at the Capitol on February 24, 2026, in Washington, DC (Andrew Harnik/Getty Images)

John Thune says strikes should deliver ‘transformational change’

Thune said that any military action should seek a broader strategic outcome in the region. 

“If you’re going to take some sort of action, I think you want to achieve a result that actually brings about the transformational change that I think we want in the region,” he said.

Thune noted that, to his knowledge, the president has not made a final determination about ordering strikes. 

“The president, I don’t think, to my knowledge, has made any decisions, but I think they’re gaming out what contingencies might look like and what’s in our national security interests,” Thune said. 

WASHINGTON, DC - JANUARY 28: U.S. Senate Majority Leader Sen. John Thune (R-SD) speaks as (L-R) Sen. Shelley Moore Capito (R-WV), Senate Majority Whip Sen. John Barrasso (R-WY), and Sen. James Lankford (R-OK) (L) listen during a news briefing after the weekly Senate Republican Policy Luncheon at the U.S. Capitol on January 28, 2026 in Washington, DC. Senate GOPs gathered for a weekly luncheon to discuss the Republican agenda. (Photo by Alex Wong/Getty Images)
Senate Majority Leader John Thune (R-SD) speaks as (L-R) Sen Shelley Moore Capito (R-WV), Senate Majority Whip Sen John Barrasso (R-WY), and Sen James Lankford (R-OK) (L) listen during a news briefing after the weekly Senate Republican Policy Luncheon at the Capitol on January 28, 2026, in Washington, DC (Alex Wong/Getty Images)

He added that preventing Iran from obtaining nuclear weapons remains the primary objective.

“Of course, first and foremost is to prevent them from having a nuclear capability, but there are also other threats that they represent in the region,” he said, pointing to the significant US military presence in surrounding waters, including the Persian Gulf, Arabian Sea and Mediterranean Sea.

Senator Ted Cruz also voiced support for taking advantage of what he described as Iran’s internal instability. Recounting a recent conversation with Trump, Cruz said, “I said, ‘Listen, the regime has never been weaker. They are teetering.’”

U.S. Sen. Ted Cruz (R-TX) speaks during a roundtable discussion on the
Sen Ted Cruz (R-TX) speaks during a roundtable discussion on the 'Take It Down Act' in the Mike Mansfield Room at the Capitol on March 03, 2025, in Washington, DC (Kayla Bartkowski/Getty Images)

“We are at a moment … where in the next six months we could realistically see the regimes in Iran, Venezuela, and Cuba all fall and we could see them replaced with governments that want to be friendly with America,” Cruz said.

He added, “If that happened, that would be the biggest geopolitical shift since the fall of the Berlin Wall.”

Nuclear talks continue as direct engagement reported in Geneva

US Special Envoy Steve Witkoff and Iranian Foreign Minister Abbas Araghchi held “direct talks” during the third round of discussions, according to a source familiar with the matter.

US Special Envoy to the Middle East Steve Witkoff delivers remarks during the swearing in ceremony for interim US Attorney for Washington, DC, Jeanine Pirro in the Oval Office of the White House on May 28, 2025, in Washington, DC (Andrew Harnik/Getty Images)
Special Envoy to the Middle East Steve Witkoff delivers remarks during the swearing-in ceremony for interim US Attorney for Washington, DC, Jeanine Pirro in the Oval Office of the White House on May 28, 2025, in Washington, DC (Andrew Harnik/Getty Images)

The source did not disclose details about the length or substance of the meeting.

Nuclear negotiations between Washington and Tehran have generally been conducted indirectly, often with mediation from Oman rather than face-to-face meetings.

Any confirmed direct contact between senior officials would represent a notable development amid heightened tensions.

U.S. President Donald Trump signs a hat, sitting next to U.S. Special Envoy Steve Witkoff (L), while watching the U.S. Open men's singles final at the Billie Jean King National Tennis Center for the U.S. Open finals on September 7, 2025 in New York City. President Trump is attending the U.S. Open men’s singles final between Carlos Alcaraz and Jannik Sinner. (Photo by Kevin Dietsch/Getty Images)
President Donald Trump signs a hat, sitting next to Special Envoy Steve Witkoff (L), while watching the US Open men's singles final at the Billie Jean King National Tennis Center for the US Open finals on September 7, 2025, in New York City (Kevin Dietsch/Getty Images)

Neither US nor Iranian officials have publicly confirmed the reported exchange. The White House has indicated that diplomatic options remain under consideration even as military assets are positioned in the region.

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