Trump calls Ozempic the 'fat drug' but says 'it hasn’t worked that well' on some of his friends

WASHINGTON, DC: President Donald Trump on Monday, September 23, shared his thoughts on weight-loss medicine Ozempic and called it a "fat drug".

The POTUS made the statement during his Monday speech in the White House, where he made an announcement on medical and scientific findings for America's children.

Trump says his friends claim they lost weight from Ozempic

During his Monday speech, Trump criticized the anti-obesity medication and said, "I call Ozempic the fat drug. Sometimes it works for people, but the ones I’ve seen it hasn’t worked that well. I have friends that are fat, and they said, 'I lost some weight,' I said, 'You don’t look it to me'."

Interestingly, this is not the first time the POTUS has made such a statement about Ozempic.

In May 2025, the POTUS shared an anecdote about a wealthy, well-known businessman friend who uses a weight-loss drug he referred to as a "fat shot".

Trump had said at the time that this "friend" was surprised by the drastic price difference for the medication, and noted that he paid only $88 for it in London, as compared to $1000 in the US.

"A friend of mine who is a businessman… Most of you would've heard of him. Highly neurotic. Brilliant businessman. Seriously overweight. And he takes the fat shot drug... I said it’s not working," the POTUS said in May. 

Interestingly, earlier this year, President Trump sparked suspicions that he could be using weight-loss drugs, such as Ozempic, as his physical examination revealed that he lost quite a lot of weight.

Experts said Trump's rapid weight loss could be due to Ozempic

Donald Trump's doctor, Sean Barbabella, claimed earlier in April 2025 that the POTUS' slim physique was because of his "active lifestyle" and "frequent victories in golf events."

However, experts believed that the president could have used Ozempic to help in weight reduction.

Obesity medicine specialist Dr Lisa Oldson informed a news publication, "Most people don’t lose weight that fast without meds."

She also admitted back in April to her speculation about the POTUS shedding that much weight only from dieting and exercise.

"When we look at people losing 30 pounds, 40 pounds, 50 pounds, 80 pounds, 100 pounds, that’s much more often due to the newer meds, the GLP agonists," Dr Oldson said, as earlier reports claimed Trump's heaviest weight reached 254 pounds.

Meanwhile, Dr Carolyn Williams, an Alabama-based dietitian, mentioned that using weight-loss drugs usually "makes you feel bad," and Trump has seemed to be happy and healthy in public.

Moreover, White House press secretary Karoline Leavitt addressed Ozempic rumors and insisted that the POTUS has had no medication in his weight-loss journey.

"As the results of his recently conducted physical concluded, President Trump is indeed in peak physical and mental condition as a result of his strenuous schedule working 20 hours per day, his exercise on the golf course, and his diet courtesy of the exceptional White House chefs," Leavitt said in a statement.