Eric Dane reveals ALS diagnosis as fans respond with references to his role from ‘Grey’s Anatomy’

LOS ANGELES, CALIFORNIA: 'Grey’s Anatomy' star Eric Dane, who is best known for his role as Dr Mark "McSteamy" Sloan, has shared that he has been diagnosed with the neurodegenerative disorder Amyotrophic Lateral Sclerosis (ALS).
Despite the life-altering news, the 51-year-old actor spoke openly about the unwavering support he’s received from his family.
Dane, who shares two daughters—15-year-old Billie Beatrice and 13-year-old Georgia Geraldine—with Rebecca Gayheart, is now entering a new chapter in his life.
The announcement has sparked an outpouring of concern and support from fans, with many referencing his role on 'Grey's Anatomy'.

Eric Dane confirms being diagnosed with ALS
Eric Dane has revealed that he has been diagnosed with Amyotrophic Lateral Sclerosis (ALS), a rare and progressive neurodegenerative disease.
Speaking to PEOPLE, the actor shared, “I have been diagnosed with ALS. I am grateful to have my loving family by my side as we navigate this next chapter.”
Despite the seriousness of the condition, Dane remains optimistic about his future. “I feel fortunate that I am able to continue working and am looking forward to returning to set of 'Euphoria' next week,” he said, while also requesting, “I kindly ask that you give my family and I privacy during this time.”
Dane, who plays Cal Jacobs on HBO’s hit drama 'Euphoria', is set to begin filming for the show’s third season on April 14.
His announcement has sparked widespread concern and support from fans, especially as he prepares to continue his work amid a difficult personal journey.

ALS, also known as Lou Gehrig’s disease, is a progressive illness that affects nerve cells in the brain and spinal cord, leading to the loss of muscle control. Early symptoms often include muscle twitching, limb weakness, and slurred speech. Over time, patients may lose the ability to move, speak, eat, and breathe.
According to the Muscular Dystrophy Association, there is no cure for ALS, and life expectancy after diagnosis typically ranges from three to five years, though some individuals have lived for decades.
Dane joins a list of public figures who have also faced the disease, including Aaron Lazar, John Driskell Hopkins, Eric Stevens, Joe Bonsall, Roberta Flack, Kenneth Mitchell, and the late Stephen Hawking.
Eric Dane's fans remember his iconic role after ALS diagnosis
After Eric Dane’s ALS diagnosis, fans were quick to reflect on his iconic 'Grey’s Anatomy' role as Mark Sloan, affectionately known as McSteamy. The beloved character, portrayed by Dane, remains one of the most memorable figures in the show's history.
One user wrote on X(formerly known as Twitter), "Why do bad things always happen to Mark Sloan? Let this man have a great life, ffs 💔💔."
Why do bad things always happen to Mark Sloan? Let this man have a great life, ffs 💔💔 https://t.co/jd6t24Ejux
— ⋆. 𐙚 (@limpbiscotto) April 11, 2025
“I very legitimately stopped watching Grey's Anatomy when they killed off Mark Sloan. The only episode I watched after that, was the beach scene that he was in. This f****n guts me. I love him,” another one added.
//I very legitimately stopped watching Grey's Anatomy when they killed off Mark Sloan. The only episode I watched after that, was the beach scene that he was in. This fuckin guts me. I love him. pic.twitter.com/ONXX6Nvcf4
— Thorn Vicious-Masen (@ViciousPrick) April 11, 2025
“This is awful. Thinking of Eric Dane and his family. McSteamy forever,” a third fan tweeted.
This is awful. Thinking of Eric Dane and his family. McSteamy forever. https://t.co/H0wK2T9eGv
— Hell On Heels (@HellOnHeelsGirl) April 11, 2025
An X user shared, "Gutted to hear about Eric Dane. Sending him and all those that love him strength."
Gutted to hear about Eric Dane. Sending him and all those that love him strength pic.twitter.com/pxzoVFwDZV
— Heather (@Heatherslosinit) April 11, 2025
A disappointed fan said, "This is absolutely gut-wrenching. Eric Dane is the epitome of professionalism and kindness and he did not deserve to have this happen to him."
This is absolutely gut-wrenching.
— The Moonlight Warrior 🌙 (@BlackMajikMan90) April 11, 2025
Eric Dane is the epitome of professionalism and kindness and he did not deserve to have this happen to him. https://t.co/5LFDqpFNBw
Another fan commented, "My heart goes out to eric dane and his family. as someone who’s grandma had ALS, this disease is terrible. those who battle with it are so strong and they fight so hard. i pray everyday there will be a cure!"
my heart goes out to eric dane and his family. as someone who’s grandma had ALS, this disease is terrible. those who battle with it are so strong and they fight so hard. i pray everyday there will be a cure.
— dixie (@thisisdixtrying) April 11, 2025
A Facebook user said, "We are really gonna lose Mark Sloan for a second time 😔😭 God damn this is heartbreaking!!!!"
Another said, "He has been a great contributor to TV and cinema. God bless him on this new chapter."
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