'Exhausted' Arizona sheriff says Nancy Guthrie search could take 'years' but 'we won’t quit'

Sheriff Chris Nanos called the search for Nancy Guthrie exhausting and said authorities continue investigating leads, including an unidentified DNA sample
Pima County Sheriff Chris Nanos updated media on the ongoing search for Nancy Guthrie (Getty Images, Jan Sonnenmair/Getty Images)
Pima County Sheriff Chris Nanos updated media on the ongoing search for Nancy Guthrie (Getty Images, Jan Sonnenmair/Getty Images)

TUSCAN, ARIZONA: The search for Nancy Guthrie, mother of NBC’s Savannah Guthrie, continues to challenge investigators, with Pima County Sheriff Chris Nanos describing the process as “exhausting.” The 84-year-old vanished two weeks ago from her Tucson home, and despite several leads, authorities have yet to locate her.

Sheriff Nanos emphasized that the investigation could take years but assured the public that his team will not give up. “Maybe it’s an hour from now. Maybe it’s weeks or months or years from now. But we won’t quit. We’re going to find Nancy. We’re going to find this guy,” Nanos told The New York Times on February 13.

Pima County Sheriff, Chris Nanos, speaks to the media on February 3, 2026 in Tucson, Arizona. He was answering questions about the search for Nancy Guthrie, the missing mother of NBC host Savannah Guthrie.(Photo by Jan Sonnenmair/Getty Images)
Pima County Sheriff Chris Nanos spoke to reporters on February 3, 2026, about the search for Nancy Guthrie (Jan Sonnenmair/Getty Images)

Sheriff describes emotional toll of ongoing search Subhead 

For 14 consecutive days, search efforts have met dead ends, leaving both authorities and the Guthrie family frustrated. Even DNA samples sent to Florida yielded no matches. Sheriff Nanos said the relentless cycle of leads that fail to materialize has taken a heavy toll.

“This has to be it, the evidence, everything’s there,” Nanos said. “Then you talk to people, you learn, you do your search, and you think, ‘Maybe not.’ It’s exhausting, these ups and downs. But we will keep moving forward.”

Investigators briefly detained delivery driver Carlos Palazuelos on February 10, hoping he could provide a lead, but he denied any knowledge of Nancy Guthrie and was released shortly afterward.

SYDNEY, AUSTRALIA - MAY 04: Australian-born presenter, Savannah Guthrie poses alongside her mother Nancy Guthrie during a production break whilst hosting NBC's
Savannah Guthrie posed with her mother Nancy during an NBC ‘Today Show’ break in Sydney, 2015 (Don Arnold/WireImage)

Authorities investigate unidentified DNA in ongoing search 

A new development came Friday when authorities reported that DNA recovered from Nancy Guthrie’s home did not match anyone considered to be in “close contact” with her. Officials have not disclosed the precise location of the sample but said deputies executed a search warrant about two miles from Guthrie’s residence following a tip.

One individual was questioned and released, while FBI agents inspected a Range Rover near a local restaurant. Authorities are continuing to search for the masked intruder reportedly seen the night Nancy disappeared. The unidentified DNA remains a critical lead, keeping investigators focused on finding the missing 84-year-old.

The investigation continues, with Sheriff Nanos vowing to maintain the search despite the emotional and procedural challenges.

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